ROR2 Antibody [ADC] - (Ozuriftamab Vedotin, Research Grade)
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-44552
Key Product Details
Species Reactivity
Human
Applications
ELISA, Flow Cytometry, Functional
Label
ADC
Antibody Source
Monoclonal Human IgG1
Concentration
LYOPH mg/ml
Product Specifications
Immunogen
ROR2 (Uniprot: Q01974)
Clonality
Monoclonal
Host
Human
Isotype
IgG1
Theoretical MW
150.25 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Description
This product is an Antibody-Drug Conjugate (ADC) for Research Use Only (RUO).
Ozuriftamab vedotin is an antibody-drug conjugate (ADC) composed of ozuriftamab, a conditionally active biologic (CAB) antibody against receptor tyrosine kinase-like orphan receptor 2 (ROR2) conjugated to monomethyl auristatin E, with potential antineoplastic activity.
This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
Ozuriftamab vedotin is an antibody-drug conjugate (ADC) composed of ozuriftamab, a conditionally active biologic (CAB) antibody against receptor tyrosine kinase-like orphan receptor 2 (ROR2) conjugated to monomethyl auristatin E, with potential antineoplastic activity.
This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
Scientific Data Images for ROR2 Antibody [ADC] - (Ozuriftamab Vedotin, Research Grade)
ELISA: ROR2 (Ozuriftamab Vedotin) Antibody - Azide and BSA Free [NBP3-44552]
Immobilized ROR2 at 2 mug/mL (30 uL/well) can bind ROR2?EC50 is 0.160 ug/mL.
Flow Cytometry: ROR2 (Ozuriftamab Vedotin) Antibody - Azide and BSA Free [NBP3-44552]
Human ROR2 CHO-S Cell Line were stained with ROR2 and negative control protein respectively, washed and then followed by PE and analyzed with FACS,The EC50 is 0.2650 mug/mL.Applications for ROR2 Antibody [ADC] - (Ozuriftamab Vedotin, Research Grade)
Application
Recommended Usage
ELISA
Optimal dilutions of this antibody should be experimentally determined.
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Functional
Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
> 90% by SDS-PAGE and HPLC
Reconstitution
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.
Formulation
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Preservative
No Preservative
Concentration
LYOPH mg/ml
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at -20C in powder form. Store at -80C once reconstituted.
Background: ROR2
Long Name
Receptor Tyrosine Kinase-like Orphan Receptor 2
Alternate Names
BDB1, NTRKR2
Additional ROR2 Products
Product Documents for ROR2 Antibody [ADC] - (Ozuriftamab Vedotin, Research Grade)
Product Specific Notices for ROR2 Antibody [ADC] - (Ozuriftamab Vedotin, Research Grade)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Loading...
Loading...
Loading...
Loading...
Loading...
Loading...
Loading...