PSG4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-33461

Novus Biologicals, part of Bio-Techne
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NBP2-33461
NBP2-33461-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PSG4 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: VSPRVKRPIENRILILPNVTRNETGPYQC

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PSG4 Antibody

PSG4 Antibody Immunohistochemistry-Paraffin: PSG4 Antibody [NBP2-33461]

Immunohistochemistry-Paraffin: PSG4 Antibody [NBP2-33461]

Staining of human skeletal muscle shows no positivity in myocytes as expected.
PSG4 Antibody Immunohistochemistry-Paraffin: PSG4 Antibody [NBP2-33461]

Immunohistochemistry-Paraffin: PSG4 Antibody [NBP2-33461]

Staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.
PSG4 Antibody Immunohistochemistry-Paraffin: PSG4 Antibody [NBP2-33461]

Immunohistochemistry-Paraffin: PSG4 Antibody [NBP2-33461]

Staining of human liver shows no positivity in hepatocytes as expected.
View 1 more images

Applications for PSG4 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PSG4

The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 (PubMed 7851896)). For additional general information about the PSG gene family, see PSG1 (MIM 176390).(supplied by OMIM)

Alternate Names

pregnancy specific beta-1-glycoprotein 4, pregnancy-specific beta-1-glycoprotein 4, PSBG-4

Gene Symbol

PSG4

UniProt

Q00888 (Human)

Additional PSG4 Products

Product Documents for PSG4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PSG4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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