PKC beta 1 Antibody [Janelia Fluor® 669]
Novus Biologicals, part of Bio-Techne | Catalog # AF3759JF669
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human, Rat
Applications
Western Blot, Immunocytochemistry
Label
Janelia Fluor 669
Antibody Source
Polyclonal Goat IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
E. coli-derived recombinant human PKC beta1
Lys607-Val671
Accession # P05771
Lys607-Val671
Accession # P05771
Specificity
Detects human and rat PKC beta1 in direct ELISAs. In direct ELISAs, less than 1% cross‑reactivity with recombinant human PKC delta is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for PKC beta 1 Antibody [Janelia Fluor® 669]
Application
Recommended Usage
Immunocytochemistry
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: PKC beta 1
Protein Kinase C (PKC) beta 1 is a member of the PKC family of serine/threonine protein kinases. It is 671 amino acids (aa) in length with a predicted molecular mass of 77 kDa. Human PKC beta 1 shares 98% aa sequence identity with the mouse and rat orthologs. A second PKC beta splice variant, PKC beta 2, contains an alternate C-terminal sequence. Conventional PKC isoforms, including PKC beta 1, require calcium and phosphatidylserine, diacylglycerol (DAG), or exogenous phorbol esters for activation. PKC beta 1 plays a role in B cell receptor signaling and histone demethylation.
Long Name
Protein Kinase C beta 1
Alternate Names
PRKCB, PRKCB1, PRKCB2
Gene Symbol
PRKCB
Additional PKC beta 1 Products
Product Documents for PKC beta 1 Antibody [Janelia Fluor® 669]
Product Specific Notices for PKC beta 1 Antibody [Janelia Fluor® 669]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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