PDE6 beta Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-47189

Novus Biologicals, part of Bio-Techne
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NBP3-47189
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PDE6 beta Antibodies »

Product Specifications

Immunogen

phosphodiesterase 6B, cGMP-specific, rod, beta. (Uniprot# P35913)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

98 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Novus Biologicals Rabbit PDE6 beta Antibody - BSA Free (NBP3-47189) is a polyclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for PDE6 beta Antibody - BSA Free

PDE6 beta Antibody - BSA Free

Western Blot: PDE6 beta Antibody - BSA Free [NBP3-47189] -

Western Blot: PDE6 beta Antibody - BSA Free [NBP3-47189] - A549 cells were subjected to SDS PAGE followed by western blot with (PDE6 beta antibody) at dilution of 1:3000

Applications for PDE6 beta Antibody - BSA Free

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PDE6 beta

Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Long Name

Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta

Alternate Names

GMP-PDE beta, PDE6B, PDEB

Gene Symbol

PDE6B

Additional PDE6 beta Products

Product Documents for PDE6 beta Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PDE6 beta Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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