NFkB1/NFkB p105 Antibody (23GB2710)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-51194

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NBP3-51194-100ul
NBP3-51194-20ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Knockdown Validated

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # 23GB2710

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all NFkB1 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human NFkB1/NFkB p105 (Uniprot: P19838)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NFkB1/NFkB p105 Antibody (23GB2710)

NFkB1/NFkB p105 Antibody (23GB2710)

Immunocytochemistry/ Immunofluorescence: NFkB1/NFkB p105 Antibody (23GB2710)[NBP3-51194] -

Immunocytochemical staining of C2C12 cells with NFkB1/NFkB p105 antibody (1:1,000). Nuclei were stained blue with DAPI; NFkB1/NFkB p105 was stained magenta with Alexa Fluor(R) 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 um.
NFkB1/NFkB p105 Antibody (23GB2710)

Flow Cytometry: NFkB1/NFkB p105 Antibody (23GB2710)[NBP3-51194] -

Flow cytometric analysis of NFkB1/NFkB p105expression in C2C12 cells using NFkB1/NFkB p105 antibody (1:2,000). Green, isotype control; red, NFKB1.
NFkB1/NFkB p105 Antibody (23GB2710)

Western Blot: NFkB1/NFkB p105 Antibody (23GB2710)[NBP3-51194] -

Western blotting analysis using NFkB1/NFkB p105 antibody (1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (1:20,000) respectively. Image was developed using FeQ(TM) ECL Substrate Kit.

Applications for NFkB1/NFkB p105 Antibody (23GB2710)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Knockdown Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: NFkB1

Nuclear factor kappa beta (NFKB) is a transcription factor that is highly influenced by stress, free-radicals, UV light and hypoxia. Unsurprisingly, NFKB is essential for many human cancers, as it regulates the expression of many downstream proteins that regulate or modify cellular growth and development. NFKB effects on angiogenic pathways and reactive mechanisms to stress and damage are well established throughout literature. Atherosclerosis is partly attributed to the mis-regulation of NFKB in hypoxia. Arthritis is related to inflammation proteins regulated through NFKB. It also has been shown to be important in synapses in brain, leading to memory and cognitive ability or impairment. In all, NFKB is one of the fastest responding transcription factors in humans, and is likely to mediate many responsive events in diseases and injury recovery.

Long Name

Nuclear Factor Kappa-B, Subunit 1

Alternate Names

NF-kB1

Gene Symbol

NFKB1

Additional NFkB1 Products

Product Documents for NFkB1/NFkB p105 Antibody (23GB2710)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for NFkB1/NFkB p105 Antibody (23GB2710)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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