Myosin VIIa Antibody (24GB665)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-50547

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NBP3-50547-100ul
NBP3-50547-20ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # 24GB665

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Myosin VIIa Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human Myosin VIIa (Uniprot: Q13402)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Myosin VIIa Antibody (24GB665)

Myosin VIIa Antibody (24GB665)

Immunocytochemistry/ Immunofluorescence: Myosin VIIa Antibody (24GB665)[NBP3-50547] -

Immunocytochemical staining of HepG2 cells with Myosin VIIa antibody (1:1,000). Nuclei were stained blue with DAPI; Myosin VIIa was stained magenta with Alexa Fluor(R) 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 um.
Myosin VIIa Antibody (24GB665)

Flow Cytometry: Myosin VIIa Antibody (24GB665)[NBP3-50547] -

Flow cytometric analysis of Myosin VIIaexpression in HepG2 cells using Myosin VIIa antibody (1:2,000). Green, isotype control; red, MYO7A.
Myosin VIIa Antibody (24GB665)

Western Blot: Myosin VIIa Antibody (24GB665)[NBP3-50547] -

Western blotting analysis using Myosin VIIa antibody (1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (1:20,000) respectively. Image was developed using FeQ(TM) ECL Substrate Kit.

Applications for Myosin VIIa Antibody (24GB665)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Myosin VIIa

Myosin VIIa is a member of the myosin superfamily of actin-based motor proteins. Defects in the myosin VIIa gene are responsible for hearing impairment in shaker-1 (sh1) mice and causes Usher syndrome IB in humans. Usher syndrome associates congenital deafness, vestibular dysfunction, and retinitis pigmentosa and is the most common form of combined deafness and blindness. Structural features of myosin VIIa protein include an ATP binding N-terminal motor domain, a central region which possess five light-chain binding (IQ) motifs, and a C-terminal domain with three myosin tail homology (MyTH4) and talin-like homology regions.

Alternate Names

deafness, autosomal dominant 11, deafness, autosomal recessive 2, DFNA11, DFNB2, myosin VIIA, myosin-VIIa, MYOVIIA, MYU7A, USH1Bsevere))

Gene Symbol

MYO7A

Additional Myosin VIIa Products

Product Documents for Myosin VIIa Antibody (24GB665)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Myosin VIIa Antibody (24GB665)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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