MVP Antibody (24GB465)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-51438

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NBP3-51438-100ul
NBP3-51438-20ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Knockdown Validated

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # 24GB465

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MVP Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human MVP (Uniprot: Q14764)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MVP Antibody (24GB465)

MVP Antibody (24GB465)

Immunocytochemistry/ Immunofluorescence: MVP Antibody (24GB465)[NBP3-51438] -

Immunocytochemical staining of HeLa cells with MVP antibody (1:1,000). Nuclei were stained blue with DAPI; MVP was stained magenta with Alexa Fluor(R) 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 um.
MVP Antibody (24GB465)

Flow Cytometry: MVP Antibody (24GB465)[NBP3-51438] -

Flow cytometric analysis of MVPexpression in HeLa cells using MVP antibody (1:2,000). Green, isotype control; red, Major vault protein.

Applications for MVP Antibody (24GB465)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Knockdown Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: MVP

MVP encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.

Alternate Names

LRPVAULT1, Lung resistance-related protein, major vault protein

Gene Symbol

MVP

Additional MVP Products

Product Documents for MVP Antibody (24GB465)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for MVP Antibody (24GB465)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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