mtRNA polymerase Antibody (HL3068)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-48766

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-48766
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # HL3068

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all mtRNA polymerase Antibodies »

Product Specifications

Immunogen

Recombinant fragment of human mtRNA polymerase.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit mtRNA polymerase Antibody (HL3068) (NBP3-48766) is a recombinant monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for mtRNA polymerase Antibody (HL3068)

mtRNA polymerase Antibody (HL3068)

Western Blot: mtRNA polymerase Antibody (HL3068) [NBP3-48766] -

Various whole cell extracts (30 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with mtRNA polymerase antibody [HL3068] (NBP3-48766) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.

Applications for mtRNA polymerase Antibody (HL3068)

Application
Recommended Usage

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: mtRNA polymerase

POLRMT, also known as DNA-directed RNA polymerase, mitochondrial, is a 246 amino acid protein that is 28 kDa, catalyzes the transcription of mitochondrial DNA into RNA using the four ribonucleoside triphosphates as substrates. This protein is currently being studied for research on autosomal dominant progressive external ophthalmoplegia, essential thrombocythemia, ophthalmoplegia, immunodeficiency, and malaria. This protein has also shown to have interactions with TFB1M, NFKB2, ICT1, TFB2M, TFAM, and over 200 other proteins in ATP/ITP metabolism, mitochondrial gene expression, transcription from mitochondrial promoters, transcription, RNA polymerase I, RNA polymerase III, and mitochondrial transcription, gene expression, and mitochondrial transcription initiation pathways.

Long Name

DNA-directed RNA polymerase, mitochondrial

Alternate Names

EC 2.7.7.6, MtRPOL, POLRMT

Gene Symbol

POLRMT

Additional mtRNA polymerase Products

Product Documents for mtRNA polymerase Antibody (HL3068)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for mtRNA polymerase Antibody (HL3068)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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