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MSH6 Antibody (CL13844) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-43857

Novus Biologicals, part of Bio-Techne

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # CL13844

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

Product Specifications

Immunogen

This antibody was generated using a synthetic peptide of P52701, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Description

Novus Biologicals Mouse MSH6 Antibody (CL13844) - Azide and BSA Free (NBP3-24582) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for MSH6 Antibody (CL13844) - Azide and BSA Free

MSH6 Antibody (CL13844) - Azide and BSA Free Immunohistochemistry-Paraffin: MSH6 Antibody [NBP3-43857]

Immunohistochemistry-Paraffin: MSH6 Antibody [NBP3-43857]

Staining of human breast cancer (ductal carcinoma) shows strong nuclear positivity in tumor cells.
MSH6 Antibody (CL13844) - Azide and BSA Free Immunohistochemistry-Paraffin: MSH6 Antibody [NBP3-43857]

Immunohistochemistry-Paraffin: MSH6 Antibody [NBP3-43857]

Analysis in human testis and skeletal muscle tissues using NBP3-43857 antibody. Corresponding MSH6 RNA-seq data are presented for the same tissues.
MSH6 Antibody (CL13844) - Azide and BSA Free Immunohistochemistry-Paraffin: MSH6 Antibody [NBP3-43857]

Immunohistochemistry-Paraffin: MSH6 Antibody [NBP3-43857]

Staining of human colorectal cancer shows strong nuclear positivity in tumor cells.

Applications for MSH6 Antibody (CL13844) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, we recommend using Heat-Induced Epitope Retrieval (HIER) with a pH level of 6. This optimized retrieval method ensures the best results for your experiments.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS with Trehalose

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MSH6

MSH6 is a mismatch-repair protein. It plays a role in tumor suppression. Genomic mutations in MSH6 predispose to the hereditary non-polyposis colorectal cancer (HNPCC) syndrome.

Alternate Names

DNA mismatch repair protein Msh6, G/T mismatch-binding protein, GTBPHNPCC5, GTMBP, hMSH6, HSAP, mutS (E. coli) homolog 6, mutS homolog 6 (E. coli), MutS-alpha 160 kDa subunit, p160, sperm-associated protein

Gene Symbol

MSH6

Additional MSH6 Products

Product Documents for MSH6 Antibody (CL13844) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MSH6 Antibody (CL13844) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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