Detects Melanocortin 3R/MC3R in direct ELISAs and Western blots. Stains mouse Melanocortin 3R/MC3R-transfected cells but not irrelevant transfectants.

Clonality

Monoclonal

Host

Rat

Isotype

IgG_2A

Applications for Mouse Melanocortin-3 R/MC3R Antibody

Application

Recommended Usage

CyTOF-ready

Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

Flow Cytometry

0.25 µg/10⁶ cells
Sample: Mouse Melanocortin 3R/MC3R transfected HEK293 cells

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Melanocortin-3 R/MC3R

Mouse Melanocortin 3R (MC3R) is a member of the melanocortin receptor family. The 323 amino acid G-protein-coupled 7-transmembrane glycoprotein is expressed in the brain where, along with MC4R, it binds alpha, beta and gamma melanocyte stimulating hormones and is involved in regulating energy balance. MC3R is also expressed by macrophages and plays an anti-inflammatory role in the heart and other tissues. Of the 69 aa that are extracellular, mouse MC3R shares 91% and 78% sequence identity with rat and human MC3R, respectively.

Long Name

Melanocortin 3 Receptor

Alternate Names

MC3R, Melanocortin-3R, Melanocortin3R

Entrez Gene IDs

4159 (Human); 17201 (Mouse); 29310 (Rat)

Gene Symbol

MC3R

Additional Melanocortin-3 R/MC3R Products

Product Documents for Mouse Melanocortin-3 R/MC3R Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Mouse Melanocortin-3 R/MC3R Antibody

For research use only

Citations
Reviews

Calculators
Flow Cytometry

Mouse Melanocortin-3 R/MC3R Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB3737

Key Product Details

Species Reactivity

Validated:

Cited:

Applications