MMP20 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-47082

Novus Biologicals, part of Bio-Techne
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NBP3-47082
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MMP20 Antibodies »

Product Specifications

Immunogen

matrix metallopeptidase 20. (Uniprot# O60882)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

54 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Novus Biologicals Rabbit MMP20 Antibody - BSA Free (NBP3-47082) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for MMP20 Antibody - BSA Free

MMP20 Antibody - BSA Free

Immunohistochemistry: MMP20 Antibody - BSA Free [NBP3-47082] -

Immunohistochemistry: MMP20 Antibody - BSA Free [NBP3-47082] - Immunohistochemistry of paraffin-embedded human liver cancer using (MMP20 antibody) at dilution of 1:50
MMP20 Antibody - BSA Free

Western Blot: MMP20 Antibody - BSA Free [NBP3-47082] -

Western Blot: MMP20 Antibody - BSA Free [NBP3-47082] - Mouse brain tissue were subjected to SDS PAGE followed by western blot with (MMP20 antibody) at dilution of 1:1000

Applications for MMP20 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:10-1:100

Immunohistochemistry

1:20-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: MMP20

MMP-20 (enamelysin) is a recently discovered member of the MMP family. This enzyme is involved in the degradation of the various components of the extracellular matrix (ECM) during development, haemostasis and pathological conditions. MMP-20 expression has been found to be restricted to the enamel organ and due to its unique expression pattern, may primarily be involved in the turnover of these molecules during tooth development. The enamel matrix proteins amelogenin, ameloblastin, and enamelin are expressed during the developmental time period, suggesting that MMP-20 may play a role in their hydrolysis (1). Recombinant human enamelysin is able to degrade amelogenin, the major protein component of the enamel matrix. On the basis of its degrading activity on amelogenin, and its highly restricted expression to dental tissues, we suggest that human enamelysin plays a central role in the process of tooth enamel formation (2). Enamelysin null mice do not process amelogenin properly, possesses an altered enamel matrix and rod pattern, has hypoplastic enamel that delaminates from the dentin, and has a deteriorating enamel organ morphology as development progresses (3).

Long Name

Matrix metalloproteinase-20

Alternate Names

EC 3.4.24.-, Enamelysin, MMP-20

Gene Symbol

MMP20

Additional MMP20 Products

Product Documents for MMP20 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for MMP20 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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