MIS/AMH Antibody (188103) [Allophycocyanin]
Novus Biologicals, part of Bio-Techne | Catalog # FAB1426A
Conjugate
Catalog #
Key Product Details
Species Reactivity
Mouse
Applications
Western Blot
Label
Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)
Antibody Source
Monoclonal Rat IgG2B Clone # 188103
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
E. coli-derived recombinant mouse MIS/AMH
Asp450-Arg555
Accession # P27106.1
Asp450-Arg555
Accession # P27106.1
Specificity
Detects mouse MIS/AMH in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross-react with recombinant human MIS or recombinant rat MIS.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2B
Applications for MIS/AMH Antibody (188103) [Allophycocyanin]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: MIS/AMH
Müllerian inhibiting substance (MIS), also named anti-Müllerian hormone (AMH), is a tissue-specific TGF-beta superfamily growth factor. Its expression is restricted to Sertoli cells of fetal and postnatal testis, and to granulosa cells of postnatal ovary. MIS is synthesized and secreted as a disulfide-linked homodimeric propeptide. Proteolytic cleavage is required to separate the N-terminal proregion from the C-terminal bioactive peptide. Both fragments remain associated in a non-covalent complex. The C-terminal sequence forms a cysteine knot via seven canonical cysteine residues found in TGF-beta superfamily members.
Long Name
Mullerian-inhibiting Substance/Anti-Mullerian Hormone
Alternate Names
AMH
Gene Symbol
AMH
Additional MIS/AMH Products
Product Documents for MIS/AMH Antibody (188103) [Allophycocyanin]
Product Specific Notices for MIS/AMH Antibody (188103) [Allophycocyanin]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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