L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. The Glutamate Receptor, Metabotropic, 1, (mGluR1 alpha) activates phospholipase C and participates in the central action of glutamate in the central nervous system, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.

Long Name

Metabotropic Glutamate Receptor 1

Alternate Names

GPRC1A, GRM1

Gene Symbol

GRM1

Additional mGluR1 Products

Product Documents for mGluR1 Antibody (511622) [DyLight 405]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for mGluR1 Antibody (511622) [DyLight 405]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

mGluR1 Antibody (511622) [DyLight 405]

Novus Biologicals, part of Bio-Techne | Catalog # FAB4836E

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

View all mGluR1 Antibodies »

Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Applications for mGluR1 Antibody (511622) [DyLight 405]

Immunohistochemistry

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: mGluR1