Klotho beta Antibody (NGM313) [Janelia Fluor® 646]
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-28017JF646
Key Product Details
Species Reactivity
Applications
Label
Antibody Source
Concentration
Product Specifications
Immunogen
Clonality
Host
Isotype
Applications for Klotho beta Antibody (NGM313) [Janelia Fluor® 646]
ELISA
Flow Cytometry
Functional
Formulation, Preparation, and Storage
Purification
Formulation
Preservative
Concentration
Shipping
Stability & Storage
Background: Klotho beta
Klotho beta is expressed primarily in the liver and pancreas and functions as a cofactor for FGF-19 subfamily member interactions with their receptors. It facilitates human FGF-19 (mouse FGF-15) binding to FGF R4 in the liver to inhibit bile acid synthesis. It also enhances FGF-21 binding to FGF R1c in adipocytes, leading to increased Insulin-dependent glucose uptake.
Alternate Names
Gene Symbol
Additional Klotho beta Products
Product Documents for Klotho beta Antibody (NGM313) [Janelia Fluor® 646]
Product Specific Notices for Klotho beta Antibody (NGM313) [Janelia Fluor® 646]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.