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KLHL12/C3IP1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-46374

Novus Biologicals, part of Bio-Techne
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NBP3-46374

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

kelch-like 12(Drosophila). (Uniprot# Q53G59)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit KLHL12/C3IP1 Antibody - BSA Free (NBP3-46374) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for KLHL12/C3IP1 Antibody - BSA Free

KLHL12/C3IP1 Antibody - BSA Free

Immunohistochemistry: KLHL12/C3IP1 Antibody - BSA Free [NBP3-46374] -

Immunohistochemistry: KLHL12/C3IP1 Antibody - BSA Free [NBP3-46374] - Immunohistochemistry of paraffin-embedded human testis using (KLHL12/C3IP1 antibody) at dilution of 1:100
KLHL12/C3IP1 Antibody - BSA Free

Western Blot: KLHL12/C3IP1 Antibody - BSA Free [NBP3-46374] -

Western Blot: KLHL12/C3IP1 Antibody - BSA Free [NBP3-46374] - PC-3 cells were subjected to SDS PAGE followed by western blot with (KLHL12/C3IP1 antibody) at dilution of 1:1000

Applications for KLHL12/C3IP1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:20-1:200

Immunohistochemistry

1:20-1:200

Western Blot

1:500-1:2000
Application Notes
Theoretical Molecular Weight is 53-56 kDa, 63-67 kDa

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: KLHL12/C3IP1

Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3. Component of an ubiquitin-protein E3 ligase complex which includes at least CUL3 and KLHL12. This complex interacts with DVL3 upon activation of the Wnt signaling pathway by WNT3A.

Alternate Names

C3IP1kelch-like protein 12, CUL3-interacting protein 1, DKIR, FLJ27152, kelch-like 12 (Drosophila), kelch-like protein C3IP1

Gene Symbol

KLHL12

Additional KLHL12/C3IP1 Products

Product Documents for KLHL12/C3IP1 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for KLHL12/C3IP1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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