Kininogen Antibody (236006) [Janelia Fluor® 669]
Novus Biologicals, part of Bio-Techne | Catalog # FAB15691JF669
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Western Blot, Immunoprecipitation
Label
Janelia Fluor 669
Antibody Source
Monoclonal Mouse IgG2B Clone # 236006
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Kininogen
Gln19-Ser644 (Ile581Thr) (predicted)
Accession # P01042.2
Gln19-Ser644 (Ile581Thr) (predicted)
Accession # P01042.2
Specificity
Detects human Kininogen Light Chain in direct ELISAs and Western blots. In Western blots, it reacts with the full length (amino acids 19‑644) and two forms of the light chain starting at amino acids 390 and 438, respectively, and does not react with the E. coli-expressed D5/Kininostatin. In Western blots, no cross-reactivity with recombinant human (rh) Cystatins A, B, C, D, E/M, F, S, SA, SN, rhFetuins A, B, rhHPRG, or recombinant mouse Kininogen is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Applications for Kininogen Antibody (236006) [Janelia Fluor® 669]
Application
Recommended Usage
Immunoprecipitation
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Kininogen
Kininogen, also known as 2-thiol proteinase inhibitor, is a multi-functional protein. The high molecule weight (HMW) form of kininogen is synthesized as a precursor protein (amino acid residues 1 to 644). The mature chain (residues 19 to 644) is further processed into the heavy chain (residues 19 to 380) and the light chain (residues 390 to 644) with release of the active peptide bradykinin. The heavy chain consists of three cystatin-like domains, which inhibit cysteine proteases. The light chain consists of a His-rich domain, which is associated with clotting activity.
Alternate Names
alpha 2-thiol Proteinase Inhibitor, BDK, KNG1
Gene Symbol
KNG1
Additional Kininogen Products
Product Documents for Kininogen Antibody (236006) [Janelia Fluor® 669]
Product Specific Notices for Kininogen Antibody (236006) [Janelia Fluor® 669]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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