KIF1B Antibody (24GB2890)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-50675

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 24GB2890

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all KIF1B Antibodies »

Product Specifications

Immunogen

Recombinant protein of human KIF1B (Uniprot: O60333)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Applications for KIF1B Antibody (24GB2890)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: KIF1B

The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIF1B is a member of the KIF1/Unc104 family of kinesin-like proteins that are involved in the transport of mitochondria or synaptic vesicles in axons. KIF1B is an amino-terminal-type motor protein that is ubiquitously expressed, with the most abundant levels in differentiated nerve cells. The human KIF1B gene maps to chromosome 1p36.2. Defects in axonal transport due to mutations at the KIF1B gene can underlie the human peripheral neuropathy phenotype. The mouse KIF1B gene generates an alternatively spliced transcript, which produces two isoforms, a 7.8 kb mRNA encoding a 130 kDa protein, and a 10 kb mRNA encoding a 204 kDa protein.

Alternate Names

CMT2, CMT2A, CMT2A1, HMSNII, KIAA0591FLJ23699, KIAA1448, kinesin family member 1B, kinesin superfamily protein KIF1B, kinesin-like protein KIF1B, KLP, MGC134844, NBLST1

Gene Symbol

KIF1B

Additional KIF1B Products

Product Documents for KIF1B Antibody (24GB2890)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for KIF1B Antibody (24GB2890)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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