Key Product Details

Species Reactivity

Canine

Applications

Neutralization

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Monoclonal Mouse IgG2A Clone # 247017

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all IL-6 Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant canine IL-6
Thr23-Met207
Accession # P41323

Specificity

Detects canine IL-6 in direct ELISAs. In direct ELISAs, no cross‑reactivity with recombinant mouse (rm) Cardiotrophin-1, recombinant human (rh) CLC, recombinant rat (rr) CNTF, recombinant cotton rat IL-6, recombinant equine IL-6, rhIL-6, recombinant porcine IL-6, rrIL-6, rmIL-11, rmLIF, or rmOncostatin M is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for IL-6 Antibody (247017) [Dylight 405]

Application
Recommended Usage

Neutralization

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: IL-6

IL-6 is a multifunctional cytokine that has an important role in host defense by regulating immune and inflammatory responses. It is expressed by a variety of normal and transformed cells including T cells, B cells, monocytes/macrophages, fibroblasts and various tumor cells. IL-6 has diverse biological functions, it stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues. Human IL-6 is active on murine cells but murine IL-6 is inactive on human cells.

Long Name

Interleukin 6

Alternate Names

BSF-2, BSF2, IFNB2, IL6, MGI-2A

Gene Symbol

IL6

Additional IL-6 Products

Product Documents for IL-6 Antibody (247017) [Dylight 405]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for IL-6 Antibody (247017) [Dylight 405]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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