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IL-6: Simple Plex

IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. It contributes to chronic inflammation in obesity, inflammatory bowel disease, arthritis, sepsis, and atherosclerosis. IL-6 signals through a receptor complex of IL-6 R alpha and gp130. gp130 is also a component of the receptors for CLC, CNTF, CT-1, IL-11, IL-27, LIF, and OSM. Soluble forms of IL-6 R alpha are generated by both alternative splicing and proteolytic cleavage. In a mechanism known as trans-signaling, complexes of soluble IL-6 and IL-6 R alpha elicit responses from gp130-expressing cells that lack cell surface IL-6 R alpha.

To assist researchers with their IL-6-dependent studies and further our understanding of IL-6 functions, R&D Systems, a Bio-Techne brand, offers a comprehensive range of IL-6 Antibody products, IL-6 Proteins and Enzymes, IL-6 ELISAs, IL-6 Luminex Assays and more. Use the filter on the left to drill down to the IL-6 product that best fits your needs.

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9 results for "IL-6 Simple Plex" in Products

IL-6: Simple Plex

IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. It contributes to chronic inflammation in obesity, inflammatory bowel disease, arthritis, sepsis, and atherosclerosis. IL-6 signals through a receptor complex of IL-6 R alpha and gp130. gp130 is also a component of the receptors for CLC, CNTF, CT-1, IL-11, IL-27, LIF, and OSM. Soluble forms of IL-6 R alpha are generated by both alternative splicing and proteolytic cleavage. In a mechanism known as trans-signaling, complexes of soluble IL-6 and IL-6 R alpha elicit responses from gp130-expressing cells that lack cell surface IL-6 R alpha.

To assist researchers with their IL-6-dependent studies and further our understanding of IL-6 functions, R&D Systems, a Bio-Techne brand, offers a comprehensive range of IL-6 Antibody products, IL-6 Proteins and Enzymes, IL-6 ELISAs, IL-6 Luminex Assays and more. Use the filter on the left to drill down to the IL-6 product that best fits your needs.

Show More

9 results for "IL-6 Simple Plex" in Products

Simple Plex Human IL-6 2nd Gen assay kit contains cartridge, sample diluent SD13, and wash buffer. Part # starting with ST01 ships in 2-3 days. Sample type indicated with PS (Plasma/Serum).

Simple Plex Mouse IL-6 assay kit for use on Ella automated benchtop ELISA. Contains cartridge, sample diluent SD09, and wash buffer.

Catalog #: 896256
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Control for use with Human IL-6 Simple Plex Cartridge Kit

Catalog #: 894968
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Control for use with Human IL-6 Simple Plex Cartridge Kit

Simple Plex 16x4 panel containing IL-1 beta / IL-1F2, IL-6 2nd Gen, IL-8/CXCL8, and TNF-alpha 2nd Gen with sample diluent SD13. Part # starting with ST01 ships in 2-3 days. Sample type indicated with PS (Plasma/Serum).

Simple Plex Human IL-6 3rd Gen assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Catalog #: 898307
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Control for use with Mouse IL-6 Simple Plex Cartridge Kit

Catalog #: 897129-SP

Control for use with Human IL-6 3rd Gen Simple Plex Assay Cartridge Kit

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