IL-4I1 Antibody (CL9071) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-44235

Novus Biologicals, part of Bio-Techne

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # CL9071

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all IL-4I1 Antibodies »

Product Specifications

Immunogen

This antibody was generated using a synthetic peptide of Q96RQ9, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Description

Novus Biologicals Mouse IL-4I1 Antibody (CL9071) - Azide and BSA Free (NBP2-88929) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for IL-4I1 Antibody (CL9071) - Azide and BSA Free

IL-4I1 Antibody (CL9071) - Azide and BSA Free Immunohistochemistry-Paraffin: IL-4I1 Antibody [NBP3-44235]

Immunohistochemistry-Paraffin: IL-4I1 Antibody [NBP3-44235]

Analysis in human testis and skeletal muscle tissues using NBP3-44235 antibody. Corresponding IL-4I1 RNA-seq data are presented for the same tissues.
IL-4I1 Antibody (CL9071) - Azide and BSA Free Immunohistochemistry-Paraffin: IL-4I1 Antibody [NBP3-44235]

Immunohistochemistry-Paraffin: IL-4I1 Antibody [NBP3-44235]

Staining of human kidney shows no positivity in cells in glomeruli.
IL-4I1 Antibody (CL9071) - Azide and BSA Free Immunohistochemistry-Paraffin: IL-4I1 Antibody [NBP3-44235]

Immunohistochemistry-Paraffin: IL-4I1 Antibody [NBP3-44235]

Staining of human skeletal muscle shows low positivity in myocytes as expected.
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Applications for IL-4I1 Antibody (CL9071) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS with Trehalose

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-4I1

Interleukin 4 induced protein 1 (IL-4I1), also known as protein FIG-1 and L-amino acid oxidase, is encoded by a B-cell IL-4-inducible gene, FIG1, and is highly expressed in primary metastinal B-cell lymphomas. It belongs to the flavin monoamine oxidase family, FIG1 subfamily. Enzymological characterization reveals that IL-4I1 has L-amino acid oxidase activity with preference toward aromatic amino acids. Studies have shown that hIL-4I1 inhibited the proliferation of CD3-stimulated T lymphocytes with a similar effect on CD4(+) and CD8(+) T cells. Its inhibitory effect was dependent on enzymatic activity and H2O2 production. Its restricted expression to lymphoid tissues indicates that it may play an important function in the immune system.

Long Name

Interleukin 4-induced Protein-1

Alternate Names

FIG1, IL4I1

Gene Symbol

IL4I1

Additional IL-4I1 Products

Product Documents for IL-4I1 Antibody (CL9071) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IL-4I1 Antibody (CL9071) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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