Human/Mouse Adropin Alexa Fluor® 350-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB9690U
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human, Mouse
Applications
Immunohistochemistry, Immunocytochemistry
Label
Alexa Fluor 350 (Excitation = 346 nm, Emission = 442 nm)
Antibody Source
Monoclonal Mouse IgG2B Clone # 976401
Product Specifications
Immunogen
Synthetic peptide containing human Adropin
Accession # Q6UWT2
Accession # Q6UWT2
Specificity
Detects human Adropin in direct ELISAs. Detects human and mouse Adropin in immunocytochemistry.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Applications for Human/Mouse Adropin Alexa Fluor® 350-conjugated Antibody
Application
Recommended Usage
Immunocytochemistry
Optimal dilution of this antibody should be experimentally determined.
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
Background: Adropin
Adropin (from the gene energy homeostasis-associated protein, ENHO) is a 76 amino acid peptide hormone encoded by the gene ENHO. Adropin levels are regulated by nutrition; a high fat diet in lean C57BL/6J mice produced rapid increase in ENHO expression. It is preferentially expressed in brain and has cardiovascular and metabolic roles in the periphery. Adropin plays a role in metabolic homeostasis, fatty acids metabolism control, insulin resistance prevention, Dyslipidemia and impaired glucose tolerance. Adropin level is thought to be a factor in obesity because it plays a role in regulating carbohydrate, lipid and protein metabolisms by moderating glucose-mediated insulin release. High plasma levels of Adropin are associated with heart failure and body mass index. Adropin has also been shown to preserve the blood brain barrier and improve neuronal function after intracerebral hemorrhage in mice.
Alternate Names
C9orf165, ENHO, UNQ470
Gene Symbol
ENHO
UniProt
Additional Adropin Products
Product Specific Notices for Human/Mouse Adropin Alexa Fluor® 350-conjugated Antibody
This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.
For research use only
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