Detects human LILRA1 in direct ELISAs. In direct ELISAs, 100% cross-reactivity with recombinant human (rh) LILRB1 is observed and no cross-reactivity rhILT3, 4, 5, 6, rhLIR-7 or -8 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2B

Scientific Data Images for Human LILRA1/LILRB1 APC-conjugated Antibody

Detection of LILRA1/LILRB1 in Human Blood Monocytes by Flow Cytometry.

Human peripheral blood monocytes were stained with Mouse Anti-Human LILRA1/LILRB1 APC-conjugated Monoclonal Antibody (Catalog # FAB30851A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Human LILRA1/LILRB1 APC-conjugated Antibody

Application

Recommended Usage

Flow Cytometry

10 µL/10⁶ cells
Sample: Human peripheral blood monocytes

Reviewed Applications

Read 1 review rated 5 using FAB30851A in the following applications:

Flow Cytometry (1 Review)

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: LILRA1/LILRB1

Leukocyte Immunoglobulin-like Receptor 6 (LIR-6), also called LILRA1 or CD85i, is a glycoprotein member of the LIR family of leukocyte Ig-like receptors. As an activating LIR, LIR-6 has a short cytoplasmic tail and a charged amino acid (aa) within the TM domain which interacts with FcR gamma. Both four (LIR-6a) and two (LIR-6b) Ig-like domain forms are expressed by monocytes and B cells. Human LIR-6 has no non-primate ortholog, but shows up to 80% aa identity with human ILT-1c and KIR-p91/PIR-B. A mouse homolog, gp49B2, has structural similarity but limited sequence identity.

Long Name

Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 1

Alternate Names

CD85I, LIR6, LIR-6

UniProt

O75019

Additional LILRA1/LILRB1 Products

Product Documents for Human LILRA1/LILRB1 APC-conjugated Antibody

Product Datasheets

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COA

SDS

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Product Specific Notices for Human LILRA1/LILRB1 APC-conjugated Antibody

For research use only

Citations
Reviews

Spectra Viewer
Flow Cytometry

Human LILRA1/LILRB1 APC-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB30851A

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

View all LILRA1/LILRB1 Antibodies »

Product Specifications

Immunogen

Specificity