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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Alexa Fluor Plus 594 (Excitation = 590 nm, Emission = 618 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # 215725

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human GFR alpha‑4/GDNF R alpha‑4

Specificity

Detects human GFR alpha‑4/GDNF R alpha‑4 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) GFR alpha-1, recombinant rat GFR alpha-1, rhGFR alpha-2, rhGFR alpha-3, or recombinant mouse GFR alpha-4 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: GFR alpha-4/GDNF R alpha-4

GFR alpha-4 is a member of a family of at least four cysteine-rich GPI-linked cell surface proteins that function as ligand binding subunits for the GDNF family (GDNF, neurturin, persephin and artemin). A functional receptor complex is achieved through association with the c-Ret receptor tyrosine kinase. GFR alpha-4 preferentially binds persephin.

Long Name

Glial Cell line-derived Neurotrophic Factor Receptor alpha 4

Alternate Names

GDNF R alpha-4, GFR alpha4, GFRa-4, GFRA4

Entrez Gene IDs

64096 (Human); 14588 (Mouse)

Gene Symbol

GFRA4

UniProt

Additional GFR alpha-4/GDNF R alpha-4 Products

Product Documents

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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