Human CSRP2 Alexa Fluor™ Plus 647-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # AF6196AFP647
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Alexa Fluor Plus 647 (Excitation = 658 nm, Emission = 675 nm)
Antibody Source
Polyclonal Goat IgG
Product Specifications
Specificity
Detects human CSRP2 in Western blots.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for Human CSRP2 Alexa Fluor™ Plus 647-conjugated Antibody
Application
Recommended Usage
Western Blot
Optimal dilution of this antibody should be experimentally determined.
Background: CSRP2
CSRP2 (Cysteine‑rich protein 2/CRP2; also Cysteine and Glycine‑rich protein 2, LMO‑5 and SmLIM) is a 21‑22 kDa member of the CRP family of LIM domain‑containing proteins. It is expressed in arterial smooth muscle, hepatic stellate cells and fibroblasts. CSRP2 is up‑regulated by TGF‑ beta and down‑regulated by PDGF, and appears to interact with PIAS1 and CRP2‑BP, thus promoting STAT signaling. It also binds to SRF and GATA4 to initiate smooth muscle differentiation. Human CSRP2 is 193 amino acids (aa) in length and contains two 50 aa LIM (for lin11/isl1/mec3) domains that contain two zinc‑finger motifs (aa 10‑61 and 119‑170), an NLS between aa 64‑69, and a Gly‑rich C‑terminus (aa 176‑187). Full‑length human CSRP2 shares 79% aa identity with human CSRP1.
Long Name
Cysteine-rich Protein 2
Alternate Names
CRP2, SmLIM
Gene Symbol
CSRP2
UniProt
Additional CSRP2 Products
Product Specific Notices for Human CSRP2 Alexa Fluor™ Plus 647-conjugated Antibody
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.
For research use only
Loading...
Loading...
Loading...
Loading...