Human CD38 Fluorescein-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB2404F

R&D Systems, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Fluorescein (Excitation = 488 nm, Emission = 515-545 nm)

Antibody Source

Monoclonal Mouse IgG2A Clone # 240742

View all CD38 Antibodies »

Product Specifications

Immunogen

NS0 mouse myeloma cell line transfected with human CD38
Met1-Ile300
Accession # P28907

Specificity

Detects human CD38.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for Human CD38 Fluorescein-conjugated Antibody

Detection of CD38 antibody in Whole Blood Monocytes antibody by Flow Cytometry.

Detection of CD38 in Whole Blood Monocytes by Flow Cytometry.

Whole blood monocytes were stained with Mouse Anti-Human CD38 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB2404F, filled histogram) or isotype control antibody (Catalog # IC003F, open histogram). View our protocol for Staining Membrane-associated Proteins.
Detection of CD38 antibody in Whole Blood Lymphocytes antibody by Flow Cytometry.

Detection of CD38 in Whole Blood Lymphocytes by Flow Cytometry.

Whole blood lymphocytes were stained with Mouse Anti-Human CD38 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB2404F) and Mouse Anti-Human CD3e APC-conjugated Monoclonal Antibody (Catalog # FAB100A). Quadrant markers were set based on control antibody staining . View our protocol for Staining Membrane-associated Proteins.

Detection of CD38 in Daudi cells by Flow Cytometry

Daudi cells were stained with Mouse Anti-Human CD38 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB2404F, filled histogram) or isotype control antibody (Catalog # IC003F, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Human CD38 Fluorescein-conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: Whole blood monocytes, lymphocytes and Daudi cell line.

Reviewed Applications

Read 1 review rated 4 using FAB2404F in the following applications:

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: CD38

CD38, also known as ADP-ribosyl cyclase, is a Type II integral membrane protein. The enzyme is able to transform NAD(P)+ into three different products with calcium mobilizing ability, cyclic ADP-ribose, NAADP+, and ADP-ribose (1). CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells (2, 3). Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells (4, 5).

References

  1. Schuber, F. and F.E. Lund (2004) Curr. Mol. Med. 4:249.
  2. Jackson, D.G. and J.I. Bell (1990) J. Immunol. 144:2811.
  3. Sun, L. et al. (1999) J. Cell Biol. 146:1161.
  4. Partida-Sanchez, S. et al. (2001) Nature Med. 7:1209.
  5. Kato, I. et al. (1995) J. Biol. Chem. 270:30045.

Long Name

Cluster of Differentiation 38

Alternate Names

ADP-ribosyl Cyclase, CD38, Cyclic ADP-ribose Hydrolase

Entrez Gene IDs

952 (Human); 12494 (Mouse); 25668 (Rat); 102126394 (Cynomolgus Monkey)

Gene Symbol

CD38

UniProt

P28907

Additional CD38 Products

Product Documents for Human CD38 Fluorescein-conjugated Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human CD38 Fluorescein-conjugated Antibody

For research use only

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