Human Caspr2 Biotinylated Antibody
R&D Systems, part of Bio-Techne | Catalog # BAF5145
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Biotin
Antibody Source
Polyclonal Sheep IgG
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Caspr2 isoform 1
Pro29-Ala1262
Accession # Q9UHC6
Pro29-Ala1262
Accession # Q9UHC6
Specificity
Detects human Caspr2 in Western blots.
Clonality
Polyclonal
Host
Sheep
Isotype
IgG
Applications for Human Caspr2 Biotinylated Antibody
Application
Recommended Usage
Western Blot
0.1 µg/mL
Sample: Recombinant Human Caspr2
Sample: Recombinant Human Caspr2
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Caspr2
Contactin-associated protein 2 (Caspr2) is a neuronal membrane protein and member of the neurexin family. Caspr2 is the mammalian homolog of Drosophila Neurexin IV. Caspr2 is believed to be involved in the local differentiation of the axon into distinct functional subdomains. Studies have shown that Caspr2 is essential for clustering of Shaker-type K+ channels in the juxtaparanodes of Ranvier. This effect is dependent on the association of Caspr2 with TAG-1, a glycosyl-phosphatidyl-inositol-anchored cell adhesion molecule. Mutations in Caspr2 are associated with the development of autism and related disorders.
Long Name
Contactin Associated Protein-like 2
Alternate Names
CDFE, CNTNAP2, NRXN4
Gene Symbol
CNTNAP2
UniProt
Additional Caspr2 Products
Product Documents for Human Caspr2 Biotinylated Antibody
Product Specific Notices for Human Caspr2 Biotinylated Antibody
For research use only
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