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Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: AGTR-2

AGTR-2, also known as AT2, is a 7-transmembrane protein that belongs to family 1 of G protein-coupled receptors. Both AGTR-2 and AGTR‑1 bind Angiotensin II and function in the control of hemodynamics. In contrast to AGTR‑1, which promotes vasoconstriction and cell proliferation, AGTR-2 inhibits growth and promotes apoptosis. In addition, Angiotensin II-induced AGTR-2 signaling induces the release of nitric oxide in the heart, kidney, and brain and participates in tissue morphogenesis and repair. Human AGTR-2 shares 92% amino acid sequence identity with mouse and rat AGTR-2.

Long Name

Angiostensin II Type 2 Receptor

Alternate Names

AGTR2, AT2, AT2R, MRX88

Entrez Gene IDs

186 (Human); 11609 (Mouse); 24182 (Rat)

Gene Symbol

AGTR2

UniProt

P50052

Additional AGTR-2 Products

Product Documents

Product Datasheets

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COA

SDS

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Product Specific Notices for Human AGTR-2 Alexa Fluor™ Plus 594-conjugated Antibody

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

Citations
Reviews

Human AGTR-2 Alexa Fluor™ Plus 594-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB3659AFP594

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

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Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Applications for Human AGTR-2 Alexa Fluor™ Plus 594-conjugated Antibody

CyTOF-ready

Flow Cytometry