HO-1/HMOX1/HSP32 Antibody (CL11661) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21199

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NBP3-21199-25ul
NBP3-21199-100ul
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Conjugate
Catalog #
Alexa Fluor 350
NBP3-44138AF350
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Alexa Fluor 405
NBP3-44138AF405
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Alexa Fluor 488
NBP3-44138AF488
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Alexa Fluor 532
NBP3-44138AF532
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Alexa Fluor 594
NBP3-44138AF594
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Alexa Fluor 647
NBP3-44138AF647
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Alexa Fluor 700
NBP3-44138AF700
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Alexa Fluor 750
NBP3-44138AF750
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Alexa Fluor Plus 405
NBP3-44138AFP405
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Alexa Fluor Plus 488
NBP3-44138AFP488
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Alexa Fluor Plus 555
NBP3-44138AFP555
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Alexa Fluor Plus 594
NBP3-44138AFP594
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Alexa Fluor Plus 647
NBP3-44138AFP647
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Alexa Fluor Plus 680
NBP3-44138AFP680
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Allophycocyanin
NBP3-44138APC
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Biotin
NBP3-44138B
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CoraFluor 1
NBP3-44138CL1
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DyLight 350
NBP3-44138UV
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DyLight 405
NBP3-44138V
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DyLight 488
NBP3-44138G
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DyLight 550
NBP3-44138R
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DyLight 594
NBP3-44138DL594
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DyLight 650
NBP3-44138C
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DyLight 680
NBP3-44138FR
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DyLight 755
NBP3-44138IR
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FITC
NBP3-44138F
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HRP
NBP3-44138H
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Janelia Fluor 525
NBP3-44138JF525
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Janelia Fluor 549
NBP3-44138JF549
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Janelia Fluor 646
NBP3-44138JF646
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Janelia Fluor 669
NBP3-44138JF669
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mFluor Violet 450 SE
NBP3-44138MFV450
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mFluor Violet 500 SE
NBP3-44138MFV500
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mFluor Violet 610 SE
NBP3-44138MFV610
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PE
NBP3-44138PE
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PerCP
NBP3-44138PCP
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL11661

Format

BSA Free

Concentration

1 mg/ml

View all HO-1/HMOX1/HSP32 Antibodies »

Product Specifications

Immunogen

This antibody was developed using a recombinant protein derived from P09601, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for HO-1/HMOX1/HSP32 Antibody (CL11661) - BSA Free

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody [NBP3-21199] -

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody [NBP3-21199] -

Staining of human prostate shows no positivity in glandular cells as expected.
Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody [NBP3-21199] -

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody [NBP3-21199] -

Analysis in human spleen and skeletal muscle tissues using NBP3-21199 antibody. Corresponding HMOX1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody [NBP3-21199] -

Immunohistochemistry-Paraffin: HO-1/HMOX1/HSP32 Antibody [NBP3-21199] -

Staining of human fallopian tube shows no positivity in glandular cells as expected.
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Applications for HO-1/HMOX1/HSP32 Antibody (CL11661) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:500-1:1000

Immunohistochemistry-Paraffin

1:500-1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HO-1/HMOX1/HSP32

Stressed mammalian cells up-regulate heme oxygenase 1 (HO-1), which catabolizes heme to biliverdin, carbon monoxide, and free iron. Results provide genetic evidence that up-regulation of HO-1 serves as an adaptive mechanism to protect cells from oxidative damage during stress (1). When cells are injured they release their contents, resulting in a local accumulation of free heme proteins and heme. HO-1 plays a crucial role in the inflammatory process during wound healing (2). TNFalpha accelerates inflammatory responses by down-regulating HO-1 expression in human monocytes. TNF antagonists may block this TNF-dependent suppression of HO-1 expression, resulting in an amelioration of inflammation (3).

Long Name

Heme Oxygenase 1

Alternate Names

HMOX1, HO1, HSP32

Gene Symbol

HMOX1

Additional HO-1/HMOX1/HSP32 Products

Product Documents for HO-1/HMOX1/HSP32 Antibody (CL11661) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HO-1/HMOX1/HSP32 Antibody (CL11661) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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