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Histone Deacetylase 8/HDAC8 Antibody (23GB6180)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-50466

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NBP3-50466-100ul
NBP3-50466-20ul

Key Product Details

Species Reactivity

Human

Applications

Western Blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # 23GB6180

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

A synthesized peptide derived from human Histone Deacetylase 8/HDAC8 (Uniprot: Q9BY41)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Histone Deacetylase 8/HDAC8 Antibody (23GB6180)

Histone Deacetylase 8/HDAC8 Antibody (23GB6180)

Immunocytochemistry/ Immunofluorescence: Histone Deacetylase 8/HDAC8 Antibody (23GB6180)[NBP3-50466] -

Immunocytochemical staining of HeLa cells with Histone Deacetylase 8/HDAC8 antibody (1:1,000). Nuclei were stained blue with DAPI; Histone Deacetylase 8/HDAC8 was stained magenta with Alexa Fluor(R) 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 um.
Histone Deacetylase 8/HDAC8 Antibody (23GB6180)

Flow Cytometry: Histone Deacetylase 8/HDAC8 Antibody (23GB6180)[NBP3-50466] -

Flow cytometric analysis of Histone Deacetylase 8/HDAC8expression in HeLa cells using Histone Deacetylase 8/HDAC8 antibody (1:2,000). Green, isotype control; red, Histone deacetylase 8.
Histone Deacetylase 8/HDAC8 Antibody (23GB6180)

Western Blot: Histone Deacetylase 8/HDAC8 Antibody (23GB6180)[NBP3-50466] -

Western blotting analysis using Histone Deacetylase 8/HDAC8 antibody (1:20,000) and HRP-conjugated goat anti-rabbit secondary antibody (1:20,000) respectively. Image was developed using FeQ(TM) ECL Substrate Kit.

Applications for Histone Deacetylase 8/HDAC8 Antibody (23GB6180)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Histone Deacetylase 8/HDAC8

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.

Alternate Names

HDAC8, HDACL1, RPD3

Gene Symbol

HDAC8

Additional Histone Deacetylase 8/HDAC8 Products

Product Documents for Histone Deacetylase 8/HDAC8 Antibody (23GB6180)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Histone Deacetylase 8/HDAC8 Antibody (23GB6180)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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