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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Polyclonal Goat IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

E. coli-derived recombinant human GDF‑11/BMP‑11
Asn299-Ser407
Accession # O95390

Specificity

Detects human and mouse GDF‑11/BMP‑11 in direct ELISAs and Western blots.  In direct ELISAs, no cross-reactivity with recombinant human/mouse/rat GDF-8/Myostatin and less than 1% cross-reactivity with recombinant human BMP-6 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for GDF-11/BMP-11 Antibody [PE]

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: GDF-11/BMP-11

BMP11 is encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.

Long Name

Growth Differentiation Factor 11

Alternate Names

BMP-11, BMP11, GDF11

Gene Symbol

GDF11

Additional GDF-11/BMP-11 Products

Product Documents for GDF-11/BMP-11 Antibody [PE]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GDF-11/BMP-11 Antibody [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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