Gab2 (Grb2-associated binder-2) is an adaptor protein involved in numerous intracellular signaling pathways via its interaction with receptor tyrosine kinases (RTKs), growth factors and cytokines. Gab2 is a substrate of various RTKs, including EGFR, insulin receptor, cytokine receptors as well as B and T cell antigen receptors; Gab2 acts as a docking protein for several SH2-containing proteins (1-3). Upon tyrosine phosphorylation, Gab2 interacts with SHP2 tyrosine phosphatase and GRB2 adaptor protein PI3-kinase, CrkL and SHC (4-5).

Long Name

GRB2-associated Binding Protein 2

Alternate Names

p100

Gene Symbol

GAB2

Additional GAB2 Products

Product Documents for GAB2 Antibody [HRP]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for GAB2 Antibody [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

GAB2 Antibody [HRP]

Novus Biologicals, part of Bio-Techne | Catalog # AF4877H

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

View all GAB2 Antibodies »

Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Applications for GAB2 Antibody [HRP]

Western Blot

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: GAB2