FGFR5/FGFRL1 Antibody (223003) [HRP]
Novus Biologicals, part of Bio-Techne | Catalog # FAB1899H
Conjugate
Catalog #
Key Product Details
Species Reactivity
Mouse
Applications
Western Blot
Label
HRP
Antibody Source
Monoclonal Rat IgG2B Clone # 223003
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse FGF R5/FGFRL1
Ala21-Pro374
Accession # Q91V87
Ala21-Pro374
Accession # Q91V87
Specificity
Detects mouse FGF R5/FGFRL1 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) FGF R1 alpha (IIIb), 1 alpha (IIIc), 1 beta (IIIb), 1 beta (IIIc), recombinant mouse (rm) FGF R2 alpha (IIIb), 2 alpha (IIIc), 2 beta (IIIb), 2 beta (IIIc), 3 alpha (IIIb), 3 alpha (IIIc), rmFGF R4, or rhFGF R5 is observed. Was not tested for cross-reactivity with rmFGF R5 gamma.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2B
Applications for FGFR5/FGFRL1 Antibody (223003) [HRP]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
PBS
Preservative
No Preservative
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: FGFR5/FGFRL1
FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGFR1 through 5. FGFRs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGFR1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGFR5 does not. Multiple forms of FGFR1, 2, and 3 are generated by alternative splicing.
Long Name
Fibroblast Growth Factor Receptor-like 1
Alternate Names
FGF R5, FGFRL1
Gene Symbol
FGFRL1
Additional FGFR5/FGFRL1 Products
Product Documents for FGFR5/FGFRL1 Antibody (223003) [HRP]
Product Specific Notices for FGFR5/FGFRL1 Antibody (223003) [HRP]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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