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Bcl-10 Antibody (23GB1410)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-51111

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NBP3-51111-100ul
NBP3-51111-20ul

Key Product Details

Species Reactivity

Human

Applications

Western Blot, Flow Cytometry, Knockdown Validated

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # 23GB1410

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

A synthesized peptide derived from human Bcl-10 (Uniprot: O95999)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Bcl-10 Antibody (23GB1410)

Bcl-10 Antibody (23GB1410)

Flow Cytometry: Bcl-10 Antibody (23GB1410)[NBP3-51111] -

Validation of Bcl-10 knockdown using flow cytometry. Wild-type(WT, Blue) and knockdown(KD, Green) HeLa cells were stained with Bcl-10 antibody (1:2,000) and analyzed using BD flow cytometer.
Bcl-10 Antibody (23GB1410)

Flow Cytometry: Bcl-10 Antibody (23GB1410)[NBP3-51111] -

Flow cytometric analysis of Bcl-10expression in HepG2 cells using Bcl-10 antibody (1:2,000). Green, isotype control; red, Bcl10.
Bcl-10 Antibody (23GB1410)

Western Blot: Bcl-10 Antibody (23GB1410)[NBP3-51111] -

Western blotting analysis using Bcl-10 antibody (1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (1:20,000) respectively. Image was developed using FeQ(TM) ECL Substrate Kit.

Applications for Bcl-10 Antibody (23GB1410)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Knockdown Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Bcl-10

Bcl-10 is an adaptor protein with a caspase recruitment domain (CARD) that promotes apoptosis and activates pro-caspase 9 and NF-kB (1-2). Bcl-10 also interacts with other CARD domain containing proteins including CARD9, 10, 11 and 14. Bcl-10 is found to form a complex with MALT1, a protein known to be translocated in MALT lymphomas. Bcl-10 and MALT1 play a critical role in antigen receptor

Long Name

B Cell Lymphoma/Leukemia 10

Alternate Names

Bcl10, c-E10, CARMEN, CIPER, CLAP, mE10

Gene Symbol

BCL10

Additional Bcl-10 Products

Product Documents for Bcl-10 Antibody (23GB1410)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Bcl-10 Antibody (23GB1410)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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