B-Raf Antibody (CL4004) [Allophycocyanin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-44118APC

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP3-44118AF350

Alexa Fluor 405

NBP3-44118AF405

Alexa Fluor 488

NBP3-44118AF488

Alexa Fluor 532

NBP3-44118AF532

Alexa Fluor 594

NBP3-44118AF594

Alexa Fluor 647

NBP3-44118AF647

Alexa Fluor 700

NBP3-44118AF700

Alexa Fluor 750

NBP3-44118AF750

Biotin

NBP3-44118B

CoraFluor 1

NBP3-44118CL1

DyLight 350

NBP3-44118UV

DyLight 405

NBP3-44118V

DyLight 488

NBP3-44118G

DyLight 550

NBP3-44118R

DyLight 594

NBP3-44118DL594

DyLight 650

NBP3-44118C

DyLight 680

NBP3-44118FR

DyLight 755

NBP3-44118IR

FITC

NBP3-44118F

HRP

NBP3-44118H

Janelia Fluor 525

NBP3-44118JF525

Janelia Fluor 549

NBP3-44118JF549

Janelia Fluor 646

NBP3-44118JF646

Janelia Fluor 669

NBP3-44118JF669

mFluor Violet 450 SE

NBP3-44118MFV450

mFluor Violet 500 SE

NBP3-44118MFV500

mFluor Violet 610 SE

NBP3-44118MFV610

PE

NBP3-44118PE

PerCP

NBP3-44118PCP

Forumulation

Catalog #

BSA Free

NBP2-59035

Azide and BSA Free

NBP3-44118

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin, Western Blot

Label

Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)

Antibody Source

Monoclonal Mouse IgG_2B Clone # CL4004

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all B-Raf Antibodies »

Product Specifications

Immunogen

This antibody was generated using a recombinant protein sequence of P15056, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2B

Applications for B-Raf Antibody (CL4004) [Allophycocyanin]

Application

Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: B-Raf

B-Raf, also know as c-Rmil, is a Serine/Threonine protein kinase member of the Raf family which includes Raf-1 and A-Raf. B-Raf is involved in the transduction of mitogenic signals from the cell membrane to the nucleus (1). Composed of three conserved region (CR1, CR2, CR3) B-Raf is expressed primarily in the brain and in the nervous system (2). It has been observed that MAPK is activated by B-Raf in response to nerve growth factor (3). More than 60% of malignant melanomas were found to contain a specific mutation, B-Raf (V599E) the product of which possesses constitutive kinase activity (4). Mutations in B-Raf have also been identified in lung cancer and non-Hodgkin lymphoma.

Long Name

v-Raf Murine Sarcoma Viral Oncogene Homolog B1

Alternate Names

BRaf, BRAF1, RAFB1

Gene Symbol

BRAF

Additional B-Raf Products

Product Documents for B-Raf Antibody (CL4004) [Allophycocyanin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for B-Raf Antibody (CL4004) [Allophycocyanin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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