3 results for "VEGF-C" in Products
VEGF-C Products
Vascular endothelial growth factor C (VEGF-C) is a homodimeric ligand of VEGF R3/Flt-4 and is synthesized with N- and C-terminal propeptides. Fully processed VEGF-C containing only the VEGF homology domain can additionally bind and activate VEGF R2/KDR/Flk-1. VEGF-C interactions with VEGF R3 are critical for lymphangiogenesis. Both the ligand and receptor are usually co-expressed at sites of lymphatic vessel sprouting, in the embryo, and in various pathological conditions. Over-expression of VEGF-C in tumor cells induces tumoral lymphatic hyperplasia, neoangiogenesis, and vessel sprouting, resulting in enhanced lymph flow and metastasis to regional lymph nodes.
Control for use with Human VEGF-C Simple Plex Cartridge Kit
Simple Plex 32x6 panel containing IL-10 2nd Gen, IL-2, IFN-gamma 3rd Gen, TNF-alpha 2nd Gen, IL-8/CXCL8, and IL-6 3rd Gen with sample diluent SD13, and wash buffer. Sample type indicated with PS (Plasma/Serum).
Simple Plex Human VEGF-C assay kit for use on Ella instrument. Contains cartridge, sample diluent SD10, and wash buffer. Sample type indicated with PS (Plasma/Serum).
Simple Plex cartridges are custom built to fit your needs. Choose from over 350 assays spanning human, mouse, rat, and non-human primate. Just select your sample type, cartridge size (16, 32, or 72 samples), and add up to 8 analytes per cartridge.