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5 results for "TLR4 Small Molecules and Peptides" in Products
TLR4 Small Molecules and Peptides
TLR4, also known as CD284, is a 100 kDa transmembrane pattern recognition receptor. It associates with MD-2 on monocytes, macrophages, dendritic cells, and B cells where it functions as a receptor for bacterial endotoxin/lipopolysaccharide (LPS). LPS is extracted from circulating CD14-LPS complexes and triggers a TLR4 mediated inflammatory response.
Reactivity:
Human, Mouse, Rat
Applications:
B/N, Flow, Func
Immunomodulator; reduces production of pro-inflammatory cytokines
Chemical Name:
4,5-Dihydro-3-phenyl-5-isoxazoleacetic acid
Purity:
≥98%
TLR4 inhibitor
Alternate Names:
TLR4-IN-C34
Chemical Name:
1-Methylethyl 2-(acetylamino)-2-deoxy-α-D-glucopyranoside 3,4,6-triacetate
TLR4 signaling inhibitor
Chemical Name:
(R)-Ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate
Purity:
≥98%
