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4 results for "TIMP-2" in Products

TIMP-2 Products

TIMP-2 (tissue inhibitor of metalloproteinases 2) is one of several TIMPs that form complexes with matrix metalloproteinases (MMPs) and inhibit their proteolytic activity. MMPs play an important role in many normal physiological processes such as embryonic development, morphogenesis, reproduction and tissue remodeling. They also participate in many pathological processes such as arthritis, cancer and cardiovascular disease. TIMP-2 binding to pro-MMP-2 is essential for the cell surface activation of pro-MMP-2 by active MMP-14 (MT1-MMP). TIMP-2 also suppresses EGF-mediated mitogenic signaling by short-circuiting EGF R activation.

Simple Plex Human TIMP-2 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer. Sample type indicated with PS (Plasma/Serum).

Reactivity:
Human
Applications:
Simple Plex
Ella Automated ELISA Platform and Simple Plex Human TIMP-2 Assay
(3)

Control for use with Human and Non-Human Primate TIMP-2 Simple Plex Assay Cartridge Kit

Reactivity:
Human, Non-human Primate
Applications:
Ctrl, Simple Plex

Simple Plex Non-Human Primate TIMP-2 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer. Sample type indicated by NP (Plasma/Serum).

Reactivity:
Non-human Primate
Applications:
Simple Plex
(3)

Simple Plex Human HE4/WFDC2 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer. Sample type indicated with PS (Plasma/Serum).

Reactivity:
Human
Applications:
Simple Plex
Human HE4 Simple Plex Assay
(3)
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