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11 results for "TIMP-2 ELISA Kits" in Products
TIMP-2 ELISA Kits
TIMP-2 (tissue inhibitor of metalloproteinases 2) is one of several TIMPs that form complexes with matrix metalloproteinases (MMPs) and inhibit their proteolytic activity. MMPs play an important role in many normal physiological processes such as embryonic development, morphogenesis, reproduction and tissue remodeling. They also participate in many pathological processes such as arthritis, cancer and cardiovascular disease. TIMP-2 binding to pro-MMP-2 is essential for the cell surface activation of pro-MMP-2 by active MMP-14 (MT1-MMP). TIMP-2 also suppresses EGF-mediated mitogenic signaling by short-circuiting EGF R activation.
Reactivity:
Human
Assay Range:
0.156-10 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva, Urine)
Applications:
ELISA
Reactivity:
Human
Assay Range:
31.2-2000 pg/mL
Applications:
ELISA
Reactivity:
Mouse
Assay Range:
7.81-500 pg/mL
Applications:
ELISA
For use with catalog number DTM200
Reactivity:
Human
Applications:
ELISA, Ctrl
Reactivity:
Rat
Assay Range:
0.63 - 40 ng/mL
Applications:
ELISA
Reactivity:
Bovine
Assay Range:
62.5 - 4000 pg/mL (example only; lot dependent)
Applications:
ELISA
Reactivity:
Canine
Assay Range:
6.25 - 400 ng/mL (example only; lot dependent)
Applications:
ELISA
Reactivity:
Bovine
Assay Range:
62.5 - 4000 pg/mL (example only; lot dependent)
Applications:
ELISA
Reactivity:
Canine
Assay Range:
6.25 - 400 ng/mL (example only; lot dependent)
Applications:
ELISA
Reactivity:
Equine
Assay Range:
7.8 - 500 ng/mL (example only; lot dependent)
Applications:
ELISA
Reactivity:
Equine
Assay Range:
7.8 - 500 ng/mL (example only; lot dependent)
Applications:
ELISA