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2 results for "Thrombospondin-1" in Products
Thrombospondin-1 Products
Thrombospondin-1 (TSP-1) is a secreted homotrimeric protein that regulates a wide range of cellular functions including their interactions with other cells and with the extracellular matrix (ECM). TSP-1 counteracts the angiogenic, hypotensive, and anti-thrombotic effects of nitric oxide (NO). It binds and neutralizes VEGF, blocks VEGF R2 signaling on vascular endothelial cells (EC), and destabilizes adhesive contacts between EC. TSP-1 also plays an important role in wound repair and tissue ...
Reactivity:
Human
Source:
NS0
Accession #:
P07996
Applications:
Bioactivity
Reactivity:
Mouse
Source:
NS0
Accession #:
NP_035710
Applications:
Bioactivity