131 results for "TBK1" in Products
TBK1 Products
NFkappaB-activating kinase (NAK) also known as TANK binding kinase-1 (TBK1) or tumor necrosis factor receptor associated factor 2-associated kinase (T2K) is a serine/threonine protein that belongs to the IkB kinase (IKK) family (1). Similar to IKK alpha and beta (2), NAK induces IkB degradation and NF-kB activity. NAK is activated by phorbol ester tumour promoters and growth factors, whereas catalytically inactive NAK specifically inhibits activation of NF-kB by protein kinase C-epsilon (PKCepsilon). NAK specifically phosphorylates IkB alpha on Serine 36 and NFkB subunit RelA (p65) on Serine 536 (3). NAK is also known to interact with TANK, TRAF-2 and TRIF (4).
| Reactivity: | Human, Mouse, Rat, Canine, Bovine |
| Details: | Mouse IgG1 kappa Monoclonal Clone #108A429 |
| Applications: | IHC, WB, ICC/IF, Flow, IP, +2 More |
![Knockout Validated: TBK1 Antibody (108A429) - BSA Free [NB100-56705]](https://resources.bio-techne.com/images/products/TBK1-Antibody-108A429-Knockout-Validated-NB100-56705-img0023.jpg "Western Blot: TBK1 Antibody (108A429) - BSA Free [NB100-56705]")
Potent TANK-binding kinase 1 (TBK1) PROTAC®
| Chemical Name: | (2S,4R)-1-((S)-18-(4-((5-Bromo-4-((3-(N-methylcyclobutanecarboxamido)propyl)amino)pyrimidin-2-yl)amino)phenoxy)-2-(tert-butyl)-4-oxo-6,10,15-trioxa-3-azaoctadecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| Purity: | ≥98% (HPLC) |
Negative control for TBK1 PROTAC® 3i (Cat. No. 7259)
| Chemical Name: | (2S,4S)-1-((S)-18-(4-((5-Bromo-4-((3-(N-methylcyclobutanecarboxamido)propyl)amino)pyrimidin-2-yl)amino)phenoxy)-2-(tert-butyl)-4-oxo-6,10,15-trioxa-3-azaoctadecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat, Canine, Bovine |
| Details: | Mouse IgG1 kappa Monoclonal Clone #108A429 |
| Applications: | IHC, WB, ICC/IF, KO, Simple Western |
![Western Blot: TBK1 Antibody (108A429)Azide and BSA Free [NBP2-33243]](https://resources.bio-techne.com/images/products/TBK1-Antibody-108A429-Azide-and-BSA-Free-Western-Blot-NBP2-33243-img0003.jpg "Western Blot: TBK1 Antibody (108A429)Azide and BSA Free [NBP2-33243]")
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | Simple Western, IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: TBK1 Antibody [NBP2-13416]](https://resources.bio-techne.com/images/products/TBK1-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-13416-img0002.jpg "Immunocytochemistry/ Immunofluorescence: TBK1 Antibody [NBP2-13416]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #4G6C7 |
| Applications: | WB, ELISA, ICC/IF, IP |
![Western Blot: TBK1 Antibody (4G6C7) [NBP3-16189]](https://resources.bio-techne.com/images/products/TBK1-Antibody-4G6C7-Western-Blot-NBP3-16189-img0005.jpg "Western Blot: TBK1 Antibody (4G6C7) [NBP3-16189]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
![Western Blot: TBK1 AntibodyAzide and BSA Free [NBP2-93921]](https://resources.bio-techne.com/images/products/TBK1-Antibody-Western-Blot-NBP2-93921-img0003.jpg "Western Blot: TBK1 AntibodyAzide and BSA Free [NBP2-93921]")
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #14D10 |
| Applications: | IHC, ELISA, Flow |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #24GB4640 |
| Applications: | WB, ICC/IF, Flow, Mycoplasma |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #S01-1G3 |
| Applications: | WB |
![Western Blot: TBK1 Antibody (S01-1G3) [NBP3-19537]](https://resources.bio-techne.com/images/products/TBK1-Antibody-S01-1G3-Western-Blot-NBP3-19537-img0001.jpg "Western Blot: TBK1 Antibody (S01-1G3) [NBP3-19537]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR2251 |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: TBK1 Antibody [NBP2-55777]](https://resources.bio-techne.com/images/products/TBK1-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-55777-img0001.jpg "Immunocytochemistry/ Immunofluorescence: TBK1 Antibody [NBP2-55777]")
| Reactivity: | Human, Mouse, Rat, Canine, Monkey, +6 More |
| Details: | Mouse IgG1 kappa Monoclonal Clone #108A429 |
| Applications: | IHC, WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #5B8P1 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #24GB4650 |
| Applications: | WB, ICC/IF, Flow, Mycoplasma |
| Reactivity: | Human, Mouse, Rat, Canine, Bovine |
| Details: | Mouse IgG1 kappa Monoclonal Clone #108A429 |
| Applications: | IHC, WB, ICC/IF, IP, KO |