4 results for "TANK Binding Kinase Inhibitors" in Products
TANK Binding Kinase Inhibitors Products
TANK binding kinase (TBK) EC 2.7.11.1 is a ubiquitously expressed serine/threonine kinase belonging to the IκB Kinase (IKK) family, which regulates NF-κB signaling. This kinase has a range of substrates, leading to involvement in multiple pathways including immune response and inflammation, autophagy, cell proliferation and growth and insulin signaling.
TBK has a critical role in innate immunity and inflammation and functions downstream of multiple interferon (IFN) inducing pathways ...
Salt inducible kinase (SIK) inhibitor; also ULK1 and 2 inhibitor
| Chemical Name: | N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
PDPK1 (PDK1) inhibitor
| Chemical Name: | N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide |
| Purity: | ≥98% (HPLC) |
Selective inhibitor of TBK
| Chemical Name: | 2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid |
| Purity: | ≥98% (HPLC) |
Potent TBK inhibitor
| Chemical Name: | N-[3-[[5-Cyclopropyl-2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
