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47 results for "stem-cell-signaling-compounds&view=expanded" in Products

Promotes HSCs expansion; increases HSCs engraftment; also endogenous prostaglandin

Alternate Names:
PGE2
Chemical Name:
(5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxo-prosta-5,13-dien-1-oic acid
Purity:
≥98%
Promotes HSCs expansion; increases HSCs engraftment; also endogenous prostaglandin

Adenylyl cyclase activator

Alternate Names:
Coleonol,Colforsin
Chemical Name:
(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one
Purity:
≥98%
Adult Stem Cell-derived Liver Organoids
(2)

Potent and selective ALK2 and ALK3 inhibitor; inhibits BMP4 signaling; promotes neural induction of hPSCs

GMP Version Available: TB6053-GMP
GMP
Alternate Names:
LDN 193189 2HCl
Chemical Name:
4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Purity:
≥98%
Application of LDN 193189 in motor neurons differentiated from iPSCs
(2)

PORCN inhibitor; inhibits Wnt processing and secretion

Chemical Name:
N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
Purity:
≥98%
iPSC-derived heart organoids differentiated with IWP 2 and CHIR 99021
(2)

Selective inhibitor of p38 MAPK

Alternate Names:
Adezmapimod
Chemical Name:
4-[5-(4-Fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]pyridine
Purity:
≥98%
Selective inhibitor of p38 MAPK

Prototypical PI 3-kinase inhibitor; also inhibits other kinases

Chemical Name:
2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride
Purity:
≥99%
Prototypical PI 3-kinase inhibitor; also inhibits other kinases

γ-secretase inhibitor; induces neuronal differentiation; blocks Notch signaling

Chemical Name:
(2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine 1,1-dimethylethyl ester
Purity:
≥99%
Using DAPT to differentiate hiPSCs into dopaminergic neurons
(2)

Wnt/β-catenin signaling inhibitor; axin stabilizer

Chemical Name:
rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide
Purity:
≥98%
Wnt/β-catenin signaling inhibitor; axin stabilizer

Potent tankyrase inhibitor

GMP Version Available: TB3748-GMP
GMP
Alternate Names:
XAV939 Wnt Signaling Inhibitor
Chemical Name:
3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one
Purity:
≥98%
Potent tankyrase inhibitor

Potent inhibitor of MEK1/2

Alternate Names:
PD325901
Chemical Name:
N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
Purity:
≥99%
Potent inhibitor of MEK1/2
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