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40 results for "SPRY4" in Products

SPRY4 Products

SPRY4 (sprouty 4) is a member of the sprouty family of proteins. It blocks tyrosine kinase growth factor activation of the MAPK signaling pathway, possibly through an interaction with either Raf1 or TESK1. Human SPRY4 is 322 amino acids (aa) in length. It contains three SH3-binding domains (aa 3-9; 25-31; 168-174), an NLS (aa 87-93), a PEST sequence (aa 118-133), and a Cys-rich/Zn++-finger domain that binds both TESK1 and Raf1 (aa 182-298). There are two variant isoforms. One is a short form ...

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Recombinant Monoclonal Antibody

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