1 result for "Sphingosine Kinase Inhibitors" in Products
Sphingosine Kinase Inhibitors Products
Sphingosine kinase (SphK) mediates the conversion of sphingosine to sphingosine-1-phosphate, a key sphingolipid signaling molecule involved in cell growth, survival, differentiation and motility. SphK constitutes an important checkpoint in the regulation of circulating levels of ceramide, sphingosine and sphingosine-1-phosphate. Two mammalian isoforms have been cloned - SPHK1 and SPHK2.
Sphingosine kinase is activated in response to pro-growth signals via GPCRs (e.g. acetylcholine muscarinic ...
Selective sphingosine kinase 2 (Sphk2) inhibitor
| Chemical Name: | (2S)-2-[3-[4-(Octyloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]-1-pyrrolidinecarboximidamide hydrochloride |
| Purity: | ≥98% (HPLC) |
