SIRP alpha/CD172a Products
Signal regulatory protein alpha (SIRP alpha, designated CD172a), also called SHPS-1 (SHP substrate 1), BIT (Brain Ig-like molecule with Tyrosine-based activation motifs) and previously, MyD-1 (Myeloid/Dendritic-1), is a transmembrane glycoprotein belonging to the SIRP/SHPS (CD172) family within the immunoglobulin superfamily. SIRP alpha contains cytoplasmic ITIM domains and produces negative regulatory signals. Through adhesion to CD47/IAP (integrin-associated protein), SIRP alpha inhibits clearance of CD47high young erythrocytes and platelets and promotes macrophage fusion during osteoclastogenesis. SIRP alpha recognition of surfactants SP-A and SP-D in the lung can inhibit alveolar macrophage cytokine production.
507 results for "SIRP alpha/CD172a" in Products
507 results for "SIRP alpha/CD172a" in Products
SIRP alpha/CD172a Products
Signal regulatory protein alpha (SIRP alpha, designated CD172a), also called SHPS-1 (SHP substrate 1), BIT (Brain Ig-like molecule with Tyrosine-based activation motifs) and previously, MyD-1 (Myeloid/Dendritic-1), is a transmembrane glycoprotein belonging to the SIRP/SHPS (CD172) family within the immunoglobulin superfamily. SIRP alpha contains cytoplasmic ITIM domains and produces negative regulatory signals. Through adhesion to CD47/IAP (integrin-associated protein), SIRP alpha inhibits clearance of CD47high young erythrocytes and platelets and promotes macrophage fusion during osteoclastogenesis. SIRP alpha recognition of surfactants SP-A and SP-D in the lung can inhibit alveolar macrophage cytokine production.
| Source: | CHO |
| Accession #: | NP_542970.1 |
| Applications: | BA |
| Reactivity: | Mouse, Rat |
| Details: | Mouse IgG2A Monoclonal Clone #OX-41 |
| Applications: | IHC, WB, ICC/IF, Flow |
![Immunohistochemistry: SIRP alpha/CD172a Antibody (OX-41) - BSA Free [NB100-65530]](https://resources.bio-techne.com/images/products/SIRP-alpha-CD172a-Antibody-OX-41-Immunohistochemistry-NB100-65530-img0007.jpg "Immunohistochemistry: SIRP alpha/CD172a Antibody (OX-41) - BSA Free [NB100-65530]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #602411 |
| Applications: | WB, Flow, CyTOF-ready, ICC |
| Source: | CHO |
| Accession #: | NP_542970.1 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | P78324.2 |
| Applications: | BA, BA |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Simple Western |
| Source: | NS0 |
| Accession #: | P97797 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI7B3 |
| Applications: | IHC, WB, Flow |
![Western Blot: SIRP alpha/CD172a Antibody (OTI7B3)Azide and BSA Free [NBP2-74197]](https://resources.bio-techne.com/images/products/SIRP-alpha-CD172a-Antibody-OTI7B3-Azide-and-BSA-Free-Western-Blot-NBP2-74197-img0001.jpg "Western Blot: SIRP alpha/CD172a Antibody (OTI7B3)Azide and BSA Free [NBP2-74197]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI7B3 |
| Applications: | IHC, WB, Flow |
![Western Blot: SIRP alpha/CD172a Antibody (OTI7B3) [NBP2-45849]](https://resources.bio-techne.com/images/products/SIRP-alpha-CD172a-Antibody-OTI7B3-Western-Blot-NBP2-45849-img0006.jpg "Western Blot: SIRP alpha/CD172a Antibody (OTI7B3) [NBP2-45849]")
| Reactivity: | Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #772734 |
| Applications: | Flow |
| Source: | CHO |
| Accession #: | NP_542970.1 |
| Applications: | BA |
| Reactivity: | Rat |
| Details: | Mouse IgG2b Monoclonal Clone #772734 |
| Applications: | WB, Flow, CyTOF-ready, Neut |
| Reactivity: | Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #602411 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #602411 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #602407 |
| Applications: | ELISA |
| Reactivity: | Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Simple Western |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #602404 |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit Monoclonal Clone #BLR049F |
| Applications: | IHC, WB, ICC/IF, IP |
![Western Blot: SIRP alpha/CD172a Antibody (BLR049F) [NBP3-14675]](https://resources.bio-techne.com/images/products/SIRP-alpha-CD172a-Antibody-Western-Blot-NBP3-14675-img0004.jpg "Western Blot: SIRP alpha/CD172a Antibody (BLR049F) [NBP3-14675]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #602411 |
| Applications: | Flow |