Proinsulin Products
Insulin is a peptide hormone that is critical for glucose homeostasis. The mature Insulin peptide is derived from Proinsulin, which includes the Insulin A and B chains connected by a peptide fragment (Insulin C-peptide). Proinsulin is processed within the endoplasmic reticulum of pancreatic β cells into equimolar ratios of mature Insulin and Insulin C-peptide. Proinsulin binds the Insulin Receptor A isoform (IR-A) with high affinity resulting in cell proliferation and migration. It has low binding affinity for the Insulin Receptor B isoform (IR-B) and the Insulin-like Growth Factor I Receptor (IGF R1).
98 results for "Proinsulin" in Products
98 results for "Proinsulin" in Products
Proinsulin Products
Insulin is a peptide hormone that is critical for glucose homeostasis. The mature Insulin peptide is derived from Proinsulin, which includes the Insulin A and B chains connected by a peptide fragment (Insulin C-peptide). Proinsulin is processed within the endoplasmic reticulum of pancreatic β cells into equimolar ratios of mature Insulin and Insulin C-peptide. Proinsulin binds the Insulin Receptor A isoform (IR-A) with high affinity resulting in cell proliferation and migration. It has low binding affinity for the Insulin Receptor B isoform (IR-B) and the Insulin-like Growth Factor I Receptor (IGF R1).
| Source: | E. coli |
| Accession #: | NP_000198 |
| Applications: | BA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #CCI-17 |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2a Monoclonal Clone #253627 |
| Applications: | IHC, CyTOF-ready, ICC, ICFlow |
| Applications: | ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2a Monoclonal Clone #253627 |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2a Monoclonal Clone #253627 |
| Applications: | ICC, ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #C-PEP-01 |
| Applications: | IHC, ELISA, ICC/IF, Func |
![Immunohistochemistry-Paraffin: Proinsulin Antibody (C-PEP-01) - BSA Free [NB500-413]](https://resources.bio-techne.com/images/products/Proinsulin-Antibody-C-PEP-01-Immunohistochemistry-Paraffin-NB500-413-img0001.jpg "Immunohistochemistry-Paraffin: Proinsulin Antibody (C-PEP-01) - BSA Free [NB500-413]")
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2a Monoclonal Clone #253627 |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2a Monoclonal Clone #253627 |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2a Monoclonal Clone #253627 |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2a Monoclonal Clone #253627 |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2a Monoclonal Clone #253627 |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2a Monoclonal Clone #253627 |
| Applications: | ICFlow |
| Applications: | ELISA |
| Applications: | ELISA |
| Applications: | ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #253627 |
| Applications: | IHC, ICC/IF, Flow, CyTOF-ready |
| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #CCI-17 |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #253627 |
| Applications: | IHC, ICC/IF, Flow, CyTOF-ready |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #253627 |
| Applications: | IHC, ICC/IF, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #C-PEP-01 |
| Applications: | IHC, ELISA, ICC/IF, Func |
![Proinsulin Antibody (C-PEP-01) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nb500-413cl1_mouse-proinsulin-mab-c-pep-01-corafluor-1-12920251514231.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #C-PEP-01 |
| Applications: | IHC, ELISA, ICC/IF, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #C-PEP-01 |
| Applications: | IHC, ELISA, ICC/IF, Func |
| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #CCI-17 |
| Applications: | WB, ELISA |
| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #CCI-17 |
| Applications: | WB, ELISA |