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4 results for "perk-inhibitors&view=expanded" in Products

Potent and selective PERK inhibitor; orally bioavailable

Chemical Name:
4-[2-Amino-4-methyl-3-(2-methyl-6-quinolinyl)benzoyl]-1,2-dihydro-1-methyl-2,5-diphenyl-3H-pyrazol-3-one hydrochloride
Purity:
≥98%
Potent and selective PERK inhibitor; orally bioavailable

Potent and selective PERK inhibitor; orally bioavailable

Chemical Name:
1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2,3-dihydro-1H-indol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone
Purity:
≥98%
Potent and selective PERK inhibitor; orally bioavailable

Potent and selective KRASG12C inhibitor

Alternate Names:
Sotorasib
Chemical Name:
(1R)-6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]pyrido[2,3-d]pyrimidin-2(1H)-one
Purity:
≥98%
Potent and selective KRASG12C inhibitor

Integrated stress response (ISR) inhibitor

Chemical Name:
N,N'-trans-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)acetamide]
Purity:
≥98%
Integrated stress response (ISR) inhibitor
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