P2X2/P2RX2: Small Molecules and Peptides
P2X2/P2RX2 belongs to the family of purinoceptors for ATP. It functions as a ligand-gated ion channel. Purinergic receptors are also expressed in spinal cord neurons and are known to cross-talk with GABA(A)Rs. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Six transcript variants encoding six distinct isoforms have been identified for this gene.
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1 result for "P2X2/P2RX2 Small Molecules and Peptides" in Products
1 result for "P2X2/P2RX2 Small Molecules and Peptides" in Products
P2X2/P2RX2: Small Molecules and Peptides
P2X2/P2RX2 belongs to the family of purinoceptors for ATP. It functions as a ligand-gated ion channel. Purinergic receptors are also expressed in spinal cord neurons and are known to cross-talk with GABA(A)Rs. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Six transcript variants encoding six distinct isoforms have been identified for this gene.
Products:
Selective, high affinity P2X3 and P2X2/3 antagonist; antinociceptive
| Chemical Name: | 5-[[[(3-Phenoxyphenyl)methyl][(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]amino]carbonyl]-1,2,4-benzenetricarboxylic acid disodium salt |
| Purity: | ≥98% (HPLC) |
