305 results for "Nicastrin" in Products
Nicastrin Products
Nicastrin (NCT) is a 150 - 160 kDa member of the nicastrin family of proteins. It is a component of the aspartyl protease γ-secretase complex and serves to stabilize and direct γ-secretase components to proper positions in the plasma membrane. The γ-secretase complex mediates the cleavage of intramembrane proteins such as notch-1 and APP. Mature human nicastrin is a 676 amino acid type I transmembrane glycoprotein. It contains a 636 aa extracellular domain (aa 34 - 669) that shows a 58 aa sequence (aa 312 - 369) which interacts with γ-secretase substrates. There are multiple splice variants of nicastrin. Over aa 34 - 669, human nicastrin shares 90% aa identity with mouse nicastrin.
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #716918 |
| Applications: | ICC |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #716918 |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #716910 |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #716910 |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #716918 |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #716918 |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #716918 |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #716918 |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #716910 |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #716918 |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #716910 |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #716910 |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #004 |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Nicastrin Antibody (004) [NBP2-89826]](https://resources.bio-techne.com/images/products/Nicastrin-Antibody-004-Immunocytochemistry-Immunofluorescence-NBP2-89826-img0001.jpg "Immunocytochemistry/ Immunofluorescence: Nicastrin Antibody (004) [NBP2-89826]")
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IHC |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #716910 |
| Applications: | WB |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IHC |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #716910 |
| Applications: | WB |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #716918 |
| Applications: | ICC |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #716918 |
| Applications: | ICC |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #716918 |
| Applications: | ICC |
Conjugate
Catalog #