NCF4 Products
The NADPH oxidase generates superoxide in phagocytic cells. It is important for immunity and its deficiency leads to chronic granulomatous disease (CGD) (1). p40-phox is a newly isolated cytosolic component of the nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase that copurifies with p67-phox. Preliminary evidence indicates that it is a component of the cytosolic complex (2). Maximal activation of NADPH oxidase requires formation of a complex between the p40-phox and p67-phox subunits via association of their PB1 domains. The crystal structure of the p40-phox/p67phox PB1 heterodimer reveals that both domains have a beta grasp topology and that they bind in a front-to-back arrangement through conserved electrostatic interactions between an acidic OPCA motif on p40-phox and basic residues in p67-phox (3).
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51 results for "NCF4" in Products
51 results for "NCF4" in Products
NCF4 Products
The NADPH oxidase generates superoxide in phagocytic cells. It is important for immunity and its deficiency leads to chronic granulomatous disease (CGD) (1). p40-phox is a newly isolated cytosolic component of the nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase that copurifies with p67-phox. Preliminary evidence indicates that it is a component of the cytosolic complex (2). Maximal activation of NADPH oxidase requires formation of a complex between the p40-phox and p67-phox subunits via association of their PB1 domains. The crystal structure of the p40-phox/p67phox PB1 heterodimer reveals that both domains have a beta grasp topology and that they bind in a front-to-back arrangement through conserved electrostatic interactions between an acidic OPCA motif on p40-phox and basic residues in p67-phox (3).
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| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B5 |
| Applications: | IHC, WB |
![Western Blot: NCF4 Antibody (OTI4B5) [NBP2-46111]](https://resources.bio-techne.com/images/products/NCF4-Antibody-4B5-Western-Blot-NBP2-46111-img0005.jpg "Western Blot: NCF4 Antibody (OTI4B5) [NBP2-46111]")
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
![Western Blot: NCF4 Antibody [NB100-61666]](https://resources.bio-techne.com/images/products/NCF4-Antibody-Western-Blot-NB100-61666-img0007.jpg "Western Blot: NCF4 Antibody [NB100-61666]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #4L9Z4 |
| Applications: | IHC, WB, IP |
![Western Blot: NCF4 Antibody (4L9Z4) [NBP3-15322]](https://resources.bio-techne.com/images/products/NCF4-Antibody-4L9Z4-Western-Blot-NBP3-15322-img0003.jpg "Western Blot: NCF4 Antibody (4L9Z4) [NBP3-15322]")
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #SR1655 |
| Applications: | IHC, WB, ICC/IF, Flow, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B5 |
| Applications: | IHC, WB |
![Western Blot: NCF4 Antibody (OTI4B5)Azide and BSA Free [NBP2-72893]](https://resources.bio-techne.com/images/products/NCF4-Antibody-OTI4B5-Azide-and-BSA-Free-Western-Blot-NBP2-72893-img0001.jpg "Western Blot: NCF4 Antibody (OTI4B5)Azide and BSA Free [NBP2-72893]")
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Catalog #
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: NCF4 Antibody [NBP2-32720]](https://resources.bio-techne.com/images/products/NCF4-Antibody-Immunohistochemistry-NBP2-32720-img0003.jpg "Immunohistochemistry-Paraffin: NCF4 Antibody [NBP2-32720]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: NCF4 Antibody [NBP2-58290]](https://resources.bio-techne.com/images/products/NCF4-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-58290-img0001.jpg "Immunocytochemistry/ Immunofluorescence: NCF4 Antibody [NBP2-58290]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: NCF4 [p Thr154] AntibodyAzide and BSA Free [NBP3-16942]](https://resources.bio-techne.com/images/products/NCF4-[p-Thr154]-Antibody-Western-Blot-NBP3-16942-img0001.jpg "Western Blot: NCF4 [p Thr154] AntibodyAzide and BSA Free [NBP3-16942]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: NCF4 Antibody [NBP2-19488]](https://resources.bio-techne.com/images/products/NCF4-Antibody-Western-Blot-NBP2-19488-img0001.jpg "Western Blot: NCF4 Antibody [NBP2-19488]")
![Western Blot: NCF4 Overexpression Lysate [NBL1-13511]](https://resources.bio-techne.com/images/products/NCF4-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-13511-img0002.jpg "Western Blot: NCF4 Overexpression Lysate [NBL1-13511]")
![Western Blot: NCF4 Overexpression Lysate [NBP2-09005]](https://resources.bio-techne.com/images/products/NCF4-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-09005-img0001.jpg "Western Blot: NCF4 Overexpression Lysate [NBP2-09005]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #3C10 |
| Applications: | ELISA |
![SDS-PAGE: Recombinant Human NCF4 His Protein [NBP2-23284]](https://resources.bio-techne.com/images/products/NCF4-Protein-SDS-Page-NBP2-23284-img0001.jpg "SDS-PAGE: Recombinant Human NCF4 His Protein [NBP2-23284]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B5 |
| Applications: | IHC, WB |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B5 |
| Applications: | IHC, WB |
![NCF4 Antibody (OTI4B5) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp2-72893cl1_mouse-ncf4-mab-oti4b5-corafluor-1-2692025165761.png "Product Feature: CoraFluor Probes for TR-FRET")
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Forumulation
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| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B5 |
| Applications: | IHC, WB |
Conjugate
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Forumulation
Catalog #
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B5 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B5 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B5 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B5 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B5 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4B5 |
| Applications: | IHC, WB |
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